MCQs BIOCHEMISTRY: Carbohydrate metabolism

1. Which mammalian cell does not have aerobic pathway
of glucose catabolism?
(a) Nerve cell (b) Sperm cell
(c) Ovum (d) Red cell
2. In aerobic glycolysis, glucose is first broken down to
pyruvate and then to CO2 and H2O in the Kreb's
cycle; but in anaerobic glycolysis it does not stop at
pyruvate but forms lactate. Why?
(a) Because pyruvate is toxic in larger concentration.
(b) Because pyruvate can form amino acid animation.
(c) Because pyruvate can form glucose back.
(d) Because this allows the regeneration of NAD from NADH2
which is formed in earlier step of glycolysis thus assuring
continuation glycolysis.
3. Which of the following step is not involved in
substrate level phosphorylation ?
(a) Dihydroxyacetone phosphate Glyceraldehyde- 3-
phosphate.
(b) 1,3- diphosphoglycerate 3-phosphoglycerate.
(c) Succinyl CoA Succinate.
(d) Phosphoenol pyruvate pyruvate.
4. How many ATP molecules are produced in the citric
acid cycle itself?
(a) One (b) Two
(c) Twelve (d) Fifteen
5. CO2 is not produced in the reaction catalysed by the
enzyme .
(a) Pyruvate dehydrogenase
(b) Succinate dehydrogenase
(c) Isocitrate dehydrogenase
(d) α- ketoglutarate dehydrogenase.
6. What is the main aim of citric acid cycle?
(a) To produce energy from carbohydrates.(b) To provide keto acids for synthesis of amino acids.
(c) To completely oxidise acetyl CoA to CO2 and H2O with
complete release of energy.
(d) To synthesize acids to maintain pH.
7. Which of the following statements is not true of HMP
shunt pathway?
(a) CO2 is not produced in it.
(b) NADPH is produced.
(c) Pentoses are produced.
(d) Does not produce ATP.
8. The utilize fructose but not glucose.
(a) Ovum
(b) Spermatozoa
(c) Adipose tissue
(d) Mammary gland.
9. Neoglucogenesis occurs predominantly from the
following compounds except .
(a) Lactate (b) Fatty acids
(c ) Glycerol (d) Amino acids
10. The uronic acid pathway is unique as it provides
to man.
(a) Ascorbic acid (b) Xylulose
(c) Glucuronic acid (d) All of these.
11. The hormone does not stimulate
hepatic glycogenolysis.
(a) Thyroxine (b) Adrenaline
(c ) Glucagon (d) Cortisol
12. Suggest a test to distinguish a case of renal
glycosuria from diabetic glycosuria.
(a) Bendict's test (b) Blood sugar
(c) Urine sugar (d) GTT.
13. NADPH serves to regenerate in red
cells to prevent their lysis.
(a) Cholesterol (b) Glutathione
(c ) NADP (d) Cysteine
14. The G-6-PD deficiency causes hemolytic anemia
due to lack of .
(a) NADPH (b) NADP
(c) Pentoses (d) Cholesterol.
15. How many ATP molecules are produced on
complete oxidation of acetyl CoA in the citric
acid cycle?
(a) Six (b) Nine
(b) Twelve (d) Fifteen.
16. Which acid acts as a carrier molecule in citric
acid cycle?
(a) Citric acid (b) Oxaloacetic acid
(c ) Succinic acid (d) Isocitric acid.
17. Which of the following compound is not a
substrate for gluconeogenesis pathway?
(a) Glycerol (b) Lactate
(c) Oxaloacetate (d) Glycogen

18. Which of the following enzyme is not involved in
gluconeogenesis?
(a) Pyruvate carboxylase
(b) Phosphoenol pyruvate
(c) Carboxykinase
(d) Hexokinase.
19. The most important initial source of blood
glucose during fasting is .
(a) Muscle glycogen
(b) Muscle protein
(c) Liver Triglyceride
(d) Liver glycogen 20. The major fate of glucose- 6- phosphate in
tissues in a well-fed state is .
(a) Hydrolysis of glucose
(b) Conversion to glycogen
(c) Isomerisation to fructose- 6- phosphate
(d) Conversion to ribulose -5- phosphate

21. The major fuel for the brain after prolonged
starvation is .
(a)Glucose (b) Fatty acids
(c) Ketone bodies (d) Glycerol
22. The monosaccharide most rapidly absorbed from
the intestine is .
(a) Glucose (b) Fructose
(c) Mannose (d) Galactose
23. Which of the following is not a polymer of
glucose?
(a) Glycogen (b) Cellulose
(c) Amylose ( d) Inulin
24. Lactose intolerance is due to-
(a) ADH deficiency
(b) Deficiency of bile
(c) Lactase deficiency
(d) Malabsorption syndrome
25. In contrast to liver, muscle glycogen does not
contribute directly to blood glucose level
because:
(a) Muscles lack glucose -6- phosphatase
(b) Muscles contain no glucokinase
(c) Muscles lack glycogen
(d) Muscles contain no glycogen phosphorylase
26. Which of the following statement is true
regarding the α- amylase?
(a) Breaks glucose from one end of the carbohydrate (b) Cleaves only α -1,4 linkages
(c) Cleaves only α -1,6 linkages
(d) All of the above.