MCQs PHARMACOLOGY: Anti-migraine agents

001. The main principle of shock treatment is: a) To increase the arterial pressure b) To increase the peripheral vascular resistance c) To increase the cardiac output d) To improve the peripheral blood flow

002. Pick out the drug which increases cardiac output: a) Noradrenalin b) Methyldopa c) Phenylephrine d) Angiotensinamide
003. Tick the synthetic vasoconstrictor having an adrenomimic effect: a) Noradrenalin b) Adrenalin c) Phenylephrine d) Angiotensinamide
004. Indicate the vasoconstrictor of endogenous origin: a) Ephedrine b) Phenylephrine c) Xylomethazoline d) Angiotensinamide
005. Which type of receptors can be activated by angiotensinamide: a) Adrenergic receptors b) Cholinergic receptors c) Dopaminergic receptors d) Angiotensin’s receptors
006. General unwanted effects of vasoconstrictors is: a) Increase of arterial pressure b) Increase of cardiac output c) Decrease of peripheral blood flow d) Increase of blood volume
007. For increasing blood pressure in case of low cardiac output the following agents must be used: a) Ganglioblockers b) Vasoconstrictors c) Positive inotropic drugs d) Diuretics
008. Tick the positive inotropic drug of glycoside structure: a) Dopamine b) Digoxin c) Dobutamine d) Adrenalin
009. Tick the positive inotropic drug of non-glycoside structure: a) Digitoxin b) Digoxin c) Dobutamine d) Strophanthin
010. Dopamine at low doses influences mainly: a) Alfa-adrenoreceptors (leads to peripheral vasoconstriction) b) Dopamine receptors (leads to vasodilation of renal and mesenterial vessels) c) Beta-1 adrenoreceptors (leads to enhanced cardiac output) d) All of the above
011. Dopamine at medium doses influences mainly: a) Alfa-adrenoreceptors (leads to peripheral vasoconstriction) b) Dopamine receptors (leads to vasodilation of renal and mesenterial vessels) c) Beta-1 adrenoreceptors (leads to enhanced cardiac output) d) All of the above
012. Dopamine in high doses influences mainly the: a) Alfa-adrenoreceptors (leads to peripheral vasoconstriction) b) Dopamine’s receptors (leads to vasodilation of renal and mesenterial vessels) c) Beta-1 adrenoreceptors (leads to enhancing of cardiac output) d) All of the above
013. Tick the group of drugs for treatment of shock with hypovolaemia (reduced circulating blood volume): a) Positive inotropic drugs b) Vasoconstrictors c) Plasmoexpanders d) Analeptics and tonics
014. Tick the group of drugs for chronic hypotension treatment: a) Positive inotropic drugs b) Vasoconstrictors c) Plasmoexpanders d) Analeptics and tonics
015. Indicate the group of drugs influencing the cerebral flow: a) Ca-channel blockers b) Derivatives of GABA c) Derivatives of Vinca minor plant d) All the above
016. Tick the drug influencing the blood flow which is related to antiplatelet agents: a) Heparin b) Aspirin c) Pyracetam d) Tanakan
017. Which of the following drugs is related to anticoagulants and may be useful in disorders of cerebral circulation? a) Aspirin b) Cinnarizine c) Nicergoline d) Heparin
018. Indicate the drugs which are Ca-channel blockers influencing the brain blood flow: a) Aminalon, Picamilon b) Nimodipine, Cinnarizine c) Heparin, Warfarin d) Vinpocetine, Nicergoline
019. Indicate the drugs influencing the blood flow in the brain - derivatives of GABA:
a) Aminalon, Picamilon b) Nimodipine, Cinnarizine c) Heparin, Warfarin d) Vinpocetine, Nicergoline
020. Indicate the drug - Vinca minor alcaloid: a) Nicergoline b) Warfarin c) Cinnarizine d) Vinpocetine
021. Tick the drug – a derivative of Ergot: a) Nicergoline b) Warfarin c) Cinnarizine d) Vinpocetine
022. Indicate the nootropic agent useful in disorders of brain circulation: a) Aspirin b) Pyracetam c) Warfarin d) All the above
023. What is the main action of GABA derivatives in disorders of brain circulation? a) Decrease of vessel permeability b) Stimulation of the metabolic processes in neurons c) Brain vessel constriction d) Intracranial pressure increase
024. Choose the appropriate mechanism of vinpocetine action: a) It dilates cerebral vessels and improves blood supply b) It constricts cerebral vessels and decreases blood supply c) It stimulates GABA-receptors and thus increases cerebral metabolic processes d) It constricts peripheral vessels and increases blood pressure 025. Antiaggregants are used in disorders of brain circulation for: a) Stimulation of the metabolic processes in neurons b) Dilation of cerebral vessels c) Improving the microcirculation in cerebral tissue d) All the above 026. Migraine is a disorder connected with: a) Thrombosis of cerebral vessels b) Brain hemorrhage c) Dysfunction of regulation of cerebral vessel tonus d) Malignant growth in brain
027. Main agents for acute migraine attack treatment are Ergot and indol derivatives and NSAID’s. The consideration is: a) True b) False
028. The following Indol derivative is used for treatment of acute migraine attack: a) Paracetamol b) Sumatriptan c) Ergotamine d) Metoclopramide
029. The following Ergot derivative is used for treatment of acute migraine attack: a) Paracetamol b) Sumatriptan c) Ergotamine d) Metoclopramide
030. The derivative of lysergic acid for migraine attack prevention is: a) Metoclopramide b) Methysergide c) Sumatriptan d) Ergotamine