MCQs PHARMACOLOGY: Antihypertensive drugs

001. This drug reduces blood pressure by acting on vasomotor centers in the CNS: a) Labetalol b) Clonidine c) Enalapril d) Nifedipine

002. All of the following are central acting antihypertensive drugs EXCEPT: a) Methyldopa b) Clonidine c) Moxonidine d) Minoxidil

003. A ganglioblocking drug for hypertension treatment is: a) Hydralazine b) Tubocurarine c) Trimethaphan d) Metoprolol

004. Pick out the sympatholythic drug: a) Labetalol b) Prazosin c) Guanethidine d) Clonidine

005. Tick the drug with nonselective beta-adrenoblocking activity: a) Atenolol b) Propranolol c) Metoprolol d) Nebivolol

006. Choose the selective blocker of beta-1 adrenoreceptors: a) Labetalol b) Prazosin c) Atenolol d) Propranolol

007. Pick out the drug – an alpha and beta adrenoreceptors blocker: a) Labetalol b) Verapamil c) Nifedipine d) Metoprolol

008. This drug inhibits the angiotensin-converting enzyme: a) Captopril b) Enalapril c) Ramipril d) All of the above

009. This drug is a directly acting vasodilator: a) Labetalol b) Clonidine c) Enalapril d) Nifedipine

010. Pick out the diuretic agent for hypertension treatment: a) Losartan b) Dichlothiazide c) Captopril d) Prazosin

011. This drug blocks alpha-1 adrenergic receptors: a) Prazosin b) Clonidine c) Enalapril d) Nifedipine

012. This drug activates alpha-2 adrenergic receptors: a) Labetalol b) Phentolamine c) Clonidine d) Enalapril

013. This drug is an inhibitor of renin synthesis: a) Propranolol b) Enalapril c) Diazoxide d) Losartan

014. This drug is a non-peptide angiotensin II receptor antagonist: a) Clonidine b) Captopril c) Losartan d) Diazoxide

015. This drug is a potassium channel activator: a) Nifedipine b) Saralasin c) Diazoxide d) Losartan

016. All of the following statements regarding angiotensin II are true EXCEPT: a) It is a peptide hormone b) It stimulates the secretion of aldosterone c) Angiotensin I is almost as potent as angiotensin II d) It is a potent vasoconstrictor

017. This drug is contraindicated in patients with bronchial asthma: a) Propranolol b) Clonidine c) Enalapril d) Nifedipine

018. This drug is converted to an active metabolite after absorption: a) Labetalol b) Clonidine c) Enalapril d) Nifedipine

019. This drug routinely produces some tachycardia: a) Propranolol b) Clonidine c) Enalapril d) Nifedipine

020. All of the following statements regarding vasodilators are true EXCEPT: a) Hydralazine causes tachycardia b) Nifedipine is a dopamine receptor antagonist c) Nitroprusside dilates both arterioles and veins d) Minoxidil can cause hypertrichosis

021. All of the following statements regarding verapamil are true EXCEPT: a) It blocks L-type calcium channels b) It increases heart rate c) It relaxes coronary artery smooth muscle d) It depresses cardiac contractility

022. Choose the unwanted effects of clonidine: a) Parkinson’s syndrome b) Sedative and hypnotic effects c) Agranulocytosis and aplastic anemia d) Dry cough and respiratory depression

023. The reason of beta-blockers administration for hypertension treatment is: a) Peripheral vasodilatation b) Diminishing of blood volume c) Decreasing of heart work d) Depression of vasomotor center

024. An endogenous vasoconstrictor that can stimulate aldosterone release from suprarenal glands: a) Angiotensinogen b) Angiotensin I c) Angiotensin II d) Angiotensin-converting enzyme

025. Choose the group of antihypertensive drugs which diminishes the metabolism of bradykinin:
a) Ganglioblockers b) Alfa-adrenoblockers c) Angiotensin-converting enzyme inhibitors d) Diuretics

026. Hydralazine (a vasodilator) can produce: a) Seizures, extrapyramidal disturbances b) Tachycardia, lupus erhythromatosis c) Acute hepatitis d) Aplastic anemia

027. Choose the vasodilator which releases NO: a) Nifedipine b) Hydralazine c) Minoxidil d) Sodium nitroprusside

028. The reason of diuretics administration for hypertension treatment is: a) Block the adrenergic transmission b) Diminishing of blood volume and amount of Na+ ions in the vessels endothelium c) Depression of rennin-angiotensin-aldosterone system d) Depression of the vasomotor center

029. Tick the diuretic agent – aldosterone antagonist: a) Furosemide b) Spironolactone c) Dichlothiazide d) Captopril
030. Tick the diuretic agent having a potent and rapid effect: a) Furosemide b) Spironolactone c) Dichlothiazide d) Indapamide PART IX Hypertensive (anti-hypotensive) drugs.