1. If you do not know how to use forum then please see this thread
    Dismiss Notice
  2. Donate for forum upgradation. Fund to raise is 140 USD Details
  3. Dismiss Notice

MCQs PHARMACOLOGY: Anxiolytic agents

Discussion in 'Exam Preparation' started by aayisha quddus, Dec 8, 2014.

Share This Page

  1. aayisha quddus

    aayisha quddus Member

    Reputation:
    15
    001. Anxiolytics are used to treat: a) Neurosis b) Psychosis c) Narcolepsy d) Bipolar disorders

    002. Anxiolytic agents should: a) Relieve pain b) Reduce anxiety and exert a calming effect c) Improve mood and behavior in patient with psychotic symptoms d) Produce drowsiness, encourage the onset and maintenance of a state of sleep

    003. Anxiolytics are also useful for: a) Treatment of epilepsy and seizures b) Insomnia c) Muscle relaxation in specific neuromuscular disorders d) All of the above

    004. Indicate the agents of choice in the treatment of most anxiety states: a) Barbiturates b) Benzodiazepines c) Lithium salts d) Phenothiazines

    005. The choice of benzodiazepines for anxiety is based on: a) A relatively high therapeutic index b) Availability of flumazenil for treatment of overdose c) A low risk of physiologic dependence d) All of the above

    006. Which of the following anxiolitics is a benzodiazepine derivative: a) Buspirone

    b) Clordiazepoxide c) Meprobamate d) Chloral hydrate

    007. Indicate the benzodiazepine, which has the shortest elimination half-life: a) Quazepam b) Triazolam c) Diazepam d) Clorazepate

    008. Which of the following benzodiazepines has the shortest duration of action? a) Triazolam b) Clorazepate c) Prazepam d) Clordiazepoxide

    009. Which of the following benzodiazepines is less likely to cause cumulative and residual effects with multiple doses? a) Clorazepate b) Quazepam c) Lorazepam d) Prazepam

    010. Anxiolytic dosage reduction is recommended: a) In patients taking cimetidine b) In patients with hepatic dysfunction c) In elderly patients d) All of the above

    011. Which of the following benzodiazepines is preferred for elderly patients? a) Clorazepate b) Clordiazepoxide c) Triazolam d) Prazepam

    012. Which of the following anxiolytics is preferred in patient with limited hepatic function? a) Buspirone b) Quazepam c) Diazepam d) Chlordiazepoxide

    013. Indicate the mechanism of hypnotic benzodiazepine action: a) Increasing the duration of the GABA-gated Cl- channel openings b) Directly activating the chloride channels c) Increasing the frequency of Cl- channel opening events d) All of the above

    014. Which of the following anxiolytics is a partial agonist of brain 5-HT1A receptors? a) Buspirone b) Alprozolam c) Chlorazepat d) Lorazepam

    015. Indicate the competitive antagonist of BZ receptors: a) Flumazenil b) Buspirone c) Picrotoxin d) Diazepam

    016. Indicate the agent, which interferes with GABA binding: a) Chlordiazepoxide b) Bicuculline c) Thiopental d) Picrotoxin

    017. Antianxiety agents have: a) Sedative and hypnotic activity b) Muscle relaxing and anticonvulsant effects c) Amnesic properties d) All of the above

    018. Which of the following disadvantages does not limit using benzodiazepines as antianxiety agents? a) Tendency to develop psychologic dependence b) A high risk of drug interactions based on liver enzyme inductionc) Synergic CNS depression with concomitant use of other drugs d) The formation of active metabolites

    019. Indicate the anxiolitic agent, which relieves anxiety without causing marked sedative effects: a) Diazepam b) Chlordiazepoxid c) Buspirone d) Clorazepate

    020. Which of the following anxiolytics has minimal abuse liability? a) Oxazepam b) Buspirone c) Flumazenil d) Alprazolam

    021. In contrast to benzodiazepines, buspirone: a) Interact directly with gabaergic system b) Has more marked hypnotic, anticonvulsant, or muscle relaxant properties c) Causes less psychomotor impairment and does not affect driving skills d) Has maximal abuse liability 022. Which of the following sedative-hypnotic drugs does not potentiate the CNS depressant effects of ethanol, phenothiazines, or tricyclic antidepressants? a) Buspirone b) Phenobarbital c) Diazepam d) Chloralhydrate

    023. Limitation of buspirone is: a) A low therapeutic index b) An extremely slow onset of action c) A high potential of development of physical dependence d) Impairment of mentation or motor functions during working hours

    024. Which drugs may be used as antianxiety agents? a) BETA-blocking drugs b) Clonidine - a partial agonist of alfa2 receptors c) Tricyclic antidepressants d) All of the above

    025. Which of the following benzodiazepines is more likely to cause “hangover” effects such as drowsiness, dysphoria, and mental or motor depression the following day? a) Oxazepam b) Triazolam c) Clorazepat d) Lorazepam

    026. Additive CNS depression can be predicted if benzodiazepines are used with: a) Ethanol b) Morphine c) Clorpromazine d) All of the above

    027. Which dosage of benzodiazepines for 60-90 days may produce severe withdrawal symptoms? a) 50-60 mg/d b) Less than 400 mg/d c) More than 800 mg/d d) Less than 40 mg/d

    028. Restlessness, anxiety, orthostatic hypotension, generalized seizures, severe tremor, vivid hallucination, and psychosis are possible symptoms of: a) Tolerance b) Withdrawal c) Drug interactions between barbiturate and diazepam d) None of the above

    029. Flumazenil is used to: a) Reverse the CNS depressant effects of hypnotic benzodiazepines overdose b) Hasten recovery following use of hypnotic benzodiazepines in anesthetic and diagnostic procedure c) Reverse benzodiazepine-induced respiratory depression d) All of the above

    030. Flumazenil given intravenously: a) Has intermediate onset and duration of action about 2 hours b) Acts rapidly but has a short half-life c) Has an effect lasting 3-5 hours d) Has duration of action longer than 6 hours
     
  2. Faraz Ahmed

    Faraz Ahmed New Member Leecher

    Reputation:
    0
    Plz upload answers.
     
Similar Threads: PHARMACOLOGY Anxiolytic
Forum Title Date
Medical Downloads (Share / Request) Pharmacology 2nd Edition Mar 8, 2015
Exam Preparation PHARMACOLOGY: ANTIVIRAL AGENTS. AGENTS FOR CHEMOTHERAPY OF CANCER Dec 9, 2014
Exam Preparation PHARMACOLOGY: ANTIPROTOZOAL AND ANTHELMINTIC DRUGS Dec 9, 2014
Exam Preparation PHARMACOLOGY: SYNTHETIC ANTIBACTERIAL DRUGS Dec 9, 2014
Exam Preparation PHARMACOLOGY: ANTIBIOTICS Dec 9, 2014

Share This Page